Direct Detection of Biotinylated Proteins by Mass Spectrometry
نویسندگان
چکیده
منابع مشابه
Direct Detection of Biotinylated Proteins by Mass Spectrometry
Mass spectrometric strategies to identify protein subpopulations involved in specific biological functions rely on covalently tagging biotin to proteins using various chemical modification methods. The biotin tag is primarily used for enrichment of the targeted subpopulation for subsequent mass spectrometry (MS) analysis. A limitation of these strategies is that MS analysis does not easily disc...
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ژورنال
عنوان ژورنال: Journal of Proteome Research
سال: 2014
ISSN: 1535-3893,1535-3907
DOI: 10.1021/pr5002862